MiT/TFE Family of Transcription Factors, Lysosomes, and Cancer.

MiT/TFE Family of Transcription Factors, Lysosomes, and Cancer.

Cancer cells have an elevated demand for power sources to help accelerated charges of development. When vitamins change into limiting, most cancers cells could change to nonconventional power sources which might be mobilized via nutrient scavenging pathways involving autophagy and the lysosome. Thus, a number of cancers are extremely reliant on constitutive activation of these …

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