Asymmetry, division of labour and the evolution of ageing in multicellular organisms

Asymmetry, division of labour and the evolution of ageing in multicellular organisms

Between the 1930s and 1960s, evolutionary geneticists labored out the fundamental rules of why organisms age. Despite a lot progress in the evolutionary biology of ageing since that point, nevertheless, many puzzles stay. The maybe most basic of these is the query of which organisms ought to exhibit senescence and which shouldn’t (or which ought to age quickly and which shouldn’t). The evolutionary origin of ageing from a non-senescent state has been conceptually framed, for instance, in phrases of the separation between germ-line and soma, the distinction between dad and mom and their offspring, and-in unicellular organisms-the unequal distribution of mobile injury at cell division.

These concepts appear to be carefully associated to the idea of ‘division of labour’ between copy and somatic upkeep. Here, we assessment these ideas and develop a toy mannequin to discover the significance of such asymmetries for the evolution of senescence. We apply our mannequin to the easiest case of a multicellular system: an organism consisting of two totipotent cells. Notably, we discover that in organisms which reproduce symmetrically and partition injury equally, senescence remains to be capable of evolve, opposite to earlier claims.

Our outcomes may need some bearing on understanding the origin of the germ-line-soma separation and the evolution of senescence in multicellular organisms and in colonial species consisting of a number of varieties of people, equivalent to, for instance, eusocial bugs with their completely different castes. This article is a component of the theme problem ‘Ageing and sociality: why, when and how does sociality change ageing patterns?’

We discovered that 300 mL drawn by means of 25-mm cellulose nitrate filters yielded higher than 5 ng/µL DNA at most websites in summer time, which was an approximate threshold for producing robust sequencing libraries in our palms. Using inferred sequence error charges, we binned 12S references for 110 species on a state guidelines into 85 single-species bins and seven multispecies bins. Of 48 bins noticed by seize survey in the St. Regis, we detected eDNA per 40, with a further 4 detections flagged as potential contaminants.

Sixteen unobserved species detected by eDNA ranged from believable to implausible based mostly on distributional information, whereas six noticed species had no 12S reference sequence. Summed log-ratio compositions of eDNA-detected taxa correlated with log(CPUE) (Pearson’s R = 0.655, P < 0.001). Shifts in eDNA composition of a number of taxa and a genotypic shift in channel catfish (Ictalurus punctatus) coincided with the Hogansburg Dam, NY, USA.

In abstract, a easy filtering equipment operated by subject crews with out prior experience gave helpful summaries of eDNA composition with minimal proof of subject contamination. 12S sequencing achieved helpful taxonomic decision regardless of the quick marker size, and information exploration with commonplace bioinformatic instruments clarified taxonomic uncertainty and sources of error.

Bio-Inspired Radio-Frequency Source Localization Based on Cochlear Cross-Correlograms

 

This paper describes a bio-inspired radio frequency (RF) scene evaluation system based mostly on cross-correlating the outputs of two single-chip RF spectrum analyzers. The latter are applied utilizing digitally-programmable “RF cochlea” chips (in 65 nm CMOS) that combine a transmission-line lively cochlear mannequin, consisting of 50 parallel exponentially-spaced levels for analyzing the radio spectrum from 1.Zero to eight.Three GHz, along with an output encoding community. The encoders convert the analog outputs of all cochlear levels into parallel delta-sigma (Δ-Σ) modulated digital alerts for real-time demodulation and evaluation by a digital back-end processor.

These outputs may also be multiplied with one another to generate cochlear correlation matrices (referred to as cross-correlograms). Simulation outcomes exhibit the use of cross-correlograms for wide-range time-delay estimation and real-time multi-source localization at completely different frequencies and enter signal-to-noise (SNR) ratios. Over-the-air measurement outcomes from an experimental two-channel RF scene evaluation prototype verify the use of such time-delay estimates, that are analogous to interaural time variations (ITDs) in the auditory system, for azimuthal supply localization at 3.four GHz. In addition, variations in acquired sign energy at the two cochleas, that are analogous to interaural degree variations (ILD) in biology, are additionally used to localize RF sources.

 Asymmetry, division of labour and the evolution of ageing in multicellular organisms

Local genetic context shapes the perform of a gene regulatory community

 

Gene expression ranges are influenced by a number of coexisting molecular mechanisms. Some of these interactions, equivalent to these of transcription elements and promoters have been studied extensively. However, predicting phenotypes of gene regulatory networks stays a serious problem. Here, we use a well-defined artificial gene regulatory community to check in Escherichia coli how community phenotypes rely upon native genetic context, i.e. the genetic neighborhood of a transcription issue and its relative place.

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 280

Tie-2/ Rat Tie- 2 ELISA Kit

ELA-E0126r 96 Tests
EUR 886

Anti-Phospho-Tie-2 (Y992) antibody

STJ90597 200 µl
EUR 197
Description: Rabbit polyclonal to Phospho-Tie-2 (Y992).

Anti-Phospho-Tie-2 (Y1108) antibody

STJ90693 200 µl
EUR 197
Description: Rabbit polyclonal to Phospho-Tie-2 (Y1108).

Anti-Phospho-Tie-2 (Y1102) antibody

STJ91136 200 µl
EUR 197
Description: Rabbit polyclonal to Phospho-Tie-2 (Y1102).

Rabbit Anti-human TIE-2 antiserum #2

TIE22-S 100 ul
EUR 457

Tie-2 Antibody

45046-100ul 100ul
EUR 252

Tie-2 Antibody

45046-50ul 50ul
EUR 187

Tie-2 Antibody

DF7500 200ul
EUR 304
Description: Tie-2 Antibody detects endogenous levels of total Tie-2.

Tie- 2 Antibody

ABD7500 100 ug
EUR 438

Anti-Tie-1 antibody

STJ96014 200 µl
EUR 197
Description: Rabbit polyclonal to Tie-1.

Rabbit Anti-human TIE-1 antiserum #2

TIE12-S 100 ul
EUR 457

Rabbit Polyclonal antibody Anti-CRBN

Anti-CRBN 50 µg
EUR 349

Recombinant Mouse TIE-2 Fc Chimera

7-04192 1µg Ask for price

Recombinant Mouse TIE-2 Fc Chimera

7-04193 3µg Ask for price

Recombinant Mouse TIE-2 Fc Chimera

7-04194 100µg Ask for price

Tie-2 Blocking Peptide

DF7500-BP 1mg
EUR 195

Tie-2 Conjugated Antibody

C45046 100ul
EUR 397

Tie-2 Polyclonal Antibody

ABP56367-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from human Tie-2 around the non-phosphorylation site of Y1102
  • Applications tips:
Description: A polyclonal antibody for detection of Tie-2 from Human, Mouse. This Tie-2 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Tie-2 around the non-phosphorylation site of Y1102

Tie-2 Polyclonal Antibody

ABP56367-01ml 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from human Tie-2 around the non-phosphorylation site of Y1102
  • Applications tips:
Description: A polyclonal antibody for detection of Tie-2 from Human, Mouse. This Tie-2 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Tie-2 around the non-phosphorylation site of Y1102

Tie-2 Polyclonal Antibody

ABP56367-02ml 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from human Tie-2 around the non-phosphorylation site of Y1102
  • Applications tips:
Description: A polyclonal antibody for detection of Tie-2 from Human, Mouse. This Tie-2 antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Tie-2 around the non-phosphorylation site of Y1102

Tie-2 Polyclonal Antibody

ABP56368-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from human Tie-2 around the non-phosphorylation site of Y992
  • Applications tips:
Description: A polyclonal antibody for detection of Tie-2 from Human, Mouse. This Tie-2 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Tie-2 around the non-phosphorylation site of Y992

Tie-2 Polyclonal Antibody

ABP56368-01ml 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from human Tie-2 around the non-phosphorylation site of Y992
  • Applications tips:
Description: A polyclonal antibody for detection of Tie-2 from Human, Mouse. This Tie-2 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Tie-2 around the non-phosphorylation site of Y992

Tie-2 Polyclonal Antibody

ABP56368-02ml 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from human Tie-2 around the non-phosphorylation site of Y992
  • Applications tips:
Description: A polyclonal antibody for detection of Tie-2 from Human, Mouse. This Tie-2 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Tie-2 around the non-phosphorylation site of Y992

Tie-2 Polyclonal Antibody

ES7366-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against Tie-2 from Human/Mouse. This antibody is tested and validated for IHC, WB, ELISA, WB, ELISA

Tie-2 Polyclonal Antibody

ES7366-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against Tie-2 from Human/Mouse. This antibody is tested and validated for IHC, WB, ELISA, WB, ELISA

Tie-2 Polyclonal Antibody

ES7367-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against Tie-2 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA

Tie-2 Polyclonal Antibody

ES7367-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against Tie-2 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA

Rabbit Anti-human TIE-2 IgG #2, aff pure

TIE22-A 100 ug
EUR 482

Anti-Adiponectin Receptor 2 (mouse) Antibody

A02218-2 200ug
EUR 498
Description: Goat Polyclonal Adiponectin Receptor 2 (mouse) Antibody. Validated in IF, IHC and tested in Mouse.

Recombinant Mouse TIE-2-Fc chimeric protein

TIE26-R-100 100 ug
EUR 895

Recombinant Mouse TIE-2-Fc chimeric protein

TIE26-R-20 20 ug
EUR 286

TIE-2/CD202b Fc Chimera

PR27152 2 ug
EUR 191

Rabbit Anti-human TIE-1 IgG #2, aff pure

TIE12-A 100 ug
EUR 482

Rabbit Anti-human TIE-2 IgG #1 aff pure

TIE21-A 100 ug
EUR 482

Monoclonal Anti-human TIE-2 IgG # 3, aff pure

TIE23-M 100 ug
EUR 482

Recombinant (CHO cells) Mouse TIE-2 Fc Chimera

RP-706 10 ug
EUR 286

Human TIE-2 Control/blocking peptide #2

TIE22-P 100 ug
EUR 164

Recombinant Human TIE-2 Fc Chimera

7-04189 1µg Ask for price

Recombinant Human TIE-2 Fc Chimera

7-04190 3µg Ask for price

Recombinant Human TIE-2 Fc Chimera

7-04191 100µg Ask for price

TIE-2 Fc Chimera Protein (Recombinant)

20-abx073609
  • EUR 328.00
  • EUR 4727.00
  • EUR 230.00
  • 10 ug
  • 1 mg
  • 2 µg
  • Shipped within 5-10 working days.

TIE-2 Fc Chimera Protein (Recombinant)

20-abx073610
  • EUR 328.00
  • EUR 4727.00
  • EUR 230.00
  • 10 ug
  • 1 mg
  • 2 µg
  • Shipped within 5-10 working days.

TEK/Tie-2 ELISA KIT|Human

EF007833 96 Tests
EUR 689

Tie-2 (phospho Tyr992) Polyclonal Antibody

ABP53387-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from human Tie-2 around the phosphorylation site of Y992
  • Applications tips:
Description: A polyclonal antibody for detection of Tie-2 phospho Tyr992) from Human, Mouse. This Tie-2 phospho Tyr992) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Tie-2 around the phosphorylation site of Y992

Tie-2 (phospho Tyr992) Polyclonal Antibody

ABP53387-01ml 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from human Tie-2 around the phosphorylation site of Y992
  • Applications tips:
Description: A polyclonal antibody for detection of Tie-2 phospho Tyr992) from Human, Mouse. This Tie-2 phospho Tyr992) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Tie-2 around the phosphorylation site of Y992

Tie-2 (phospho Tyr992) Polyclonal Antibody

ABP53387-02ml 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from human Tie-2 around the phosphorylation site of Y992
  • Applications tips:
Description: A polyclonal antibody for detection of Tie-2 phospho Tyr992) from Human, Mouse. This Tie-2 phospho Tyr992) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Tie-2 around the phosphorylation site of Y992

Tie-2 (phospho Tyr1108) Polyclonal Antibody

ABP56365-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from human Tie-2 around the phosphorylation site of Y1108
  • Applications tips:
Description: A polyclonal antibody for detection of Tie-2 phospho Tyr1108) from Human, Mouse. This Tie-2 phospho Tyr1108) antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Tie-2 around the phosphorylation site of Y1108

Tie-2 (phospho Tyr1108) Polyclonal Antibody

ABP56365-01ml 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from human Tie-2 around the phosphorylation site of Y1108
  • Applications tips:
Description: A polyclonal antibody for detection of Tie-2 phospho Tyr1108) from Human, Mouse. This Tie-2 phospho Tyr1108) antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Tie-2 around the phosphorylation site of Y1108

Tie-2 (phospho Tyr1108) Polyclonal Antibody

ABP56365-02ml 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from human Tie-2 around the phosphorylation site of Y1108
  • Applications tips:
Description: A polyclonal antibody for detection of Tie-2 phospho Tyr1108) from Human, Mouse. This Tie-2 phospho Tyr1108) antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Tie-2 around the phosphorylation site of Y1108

Tie-2 (phospho Tyr1102) Polyclonal Antibody

ABP56366-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from human Tie-2 around the phosphorylation site of Y1102
  • Applications tips:
Description: A polyclonal antibody for detection of Tie-2 phospho Tyr1102) from Human, Mouse. This Tie-2 phospho Tyr1102) antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Tie-2 around the phosphorylation site of Y1102

Tie-2 (phospho Tyr1102) Polyclonal Antibody

ABP56366-01ml 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from human Tie-2 around the phosphorylation site of Y1102
  • Applications tips:
Description: A polyclonal antibody for detection of Tie-2 phospho Tyr1102) from Human, Mouse. This Tie-2 phospho Tyr1102) antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Tie-2 around the phosphorylation site of Y1102

Tie-2 (phospho Tyr1102) Polyclonal Antibody

ABP56366-02ml 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from human Tie-2 around the phosphorylation site of Y1102
  • Applications tips:
Description: A polyclonal antibody for detection of Tie-2 phospho Tyr1102) from Human, Mouse. This Tie-2 phospho Tyr1102) antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Tie-2 around the phosphorylation site of Y1102

Tie-2 (phospho Tyr1108) Polyclonal Antibody

ES7364-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against Tie-2 (phospho Tyr1108) from Human/Mouse. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA

Tie-2 (phospho Tyr1108) Polyclonal Antibody

ES7364-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against Tie-2 (phospho Tyr1108) from Human/Mouse. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA

Tie-2 (phospho Tyr1102) Polyclonal Antibody

ES7365-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against Tie-2 (phospho Tyr1102) from Human/Mouse. This antibody is tested and validated for IHC, WB, ELISA

Tie-2 (phospho Tyr1102) Polyclonal Antibody

ES7365-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against Tie-2 (phospho Tyr1102) from Human/Mouse. This antibody is tested and validated for IHC, WB, ELISA

Tie-2 (phospho Tyr992) Polyclonal Antibody

ES4386-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against Tie-2 (phospho Tyr992) from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA

Tie-2 (phospho Tyr992) Polyclonal Antibody

ES4386-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against Tie-2 (phospho Tyr992) from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA

TIE-1 Antibody

47997-100ul 100ul
EUR 333

TIE-1 Antibody

47997-50ul 50ul
EUR 239

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 280

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 280

Anti-Fascin 2/FSCN2 Antibody

A07840-2 100ug/vial
EUR 294

Anti-EIF4A1/2/3 Antibody

A03922-2 100ug/vial
EUR 334

Anti-ErbB 2/ERBB2 Antibody

A00010-2 100ug/vial
EUR 334

Anti-Bcl-2/BCL2 Antibody

A00040-2 100ug/vial
EUR 334

Anti-Angiopoietin-2/ANGPT2 Antibody

A00370-2 100ug/vial
EUR 334

Recombinant Mouse TIE-1 Fc Chimera

7-04186 1µg Ask for price

Recombinant Mouse TIE-1 Fc Chimera

7-04187 3µg Ask for price

Recombinant Mouse TIE-1 Fc Chimera

7-04188 100µg Ask for price

Anti-CCR4 (mouse) Antibody

A00755-2 200ug
EUR 397
Description: Goat Polyclonal CCR4 (mouse) Antibody. Validated in ELISA, IF, IHC and tested in Mouse.

Recombinant (Sf9) Human TIE-2 Fc Chimera

RP-705 10 ug
EUR 286

Human TIE-1 Control/blocking peptide #2

TIE12-P 100 ug
EUR 164

Human TIE-2 Control/blocking peptide #1

TIE21-P 100 ug
EUR 164

Recombinant Human TIE-2-FC chimeric protein

TIE25-R-20 20 ug
EUR 286

Anti-p56Dok-2 (Ab-299) Antibody

A07956-2 100ul
EUR 397
Description: Rabbit Polyclonal p56Dok-2 (Ab-299) Antibody. Validated in IF, IHC, WB and tested in Human.

Anti-VEGF Receptor 2/KDR Antibody

A00901-2 100ug/vial
EUR 334

Anti-Anterior Gradient 2/AGR2 Antibody

A02922-2 100ug/vial
EUR 334

Anti-COX2/Cyclooxygenase 2/PTGS2 Antibody

A00084-2 100ug/vial
EUR 294

Anti-beta 2 Microglobulin/B2m Antibody

A00456-2 100ug/vial
EUR 294

Anti-HIF-2-alpha/EPAS1 Antibody

PA1129-2 100ug/vial
EUR 294

Anti-Bcl-2 Rabbit Monoclonal Antibody

M00040-2 100ug/vial
EUR 397
Description: Rabbit Monoclonal Bcl-2 Antibody. Validated in IF, WB and tested in Human, Mouse.

Anti-Beta 2 Microglobulin Antibody (monoclonal, 2H10)

M00456-2 100ug/vial
EUR 334

TIE-1 Conjugated Antibody

C47997 100ul
EUR 397

Tie-1 Polyclonal Antibody

ABP56395-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from the Internal region of human Tie-1 at AA range: 820-900
  • Applications tips:
Description: A polyclonal antibody for detection of Tie-1 from Human, Mouse, Rat. This Tie-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Tie-1 at AA range: 820-900

Tie-1 Polyclonal Antibody

ABP56395-01ml 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from the Internal region of human Tie-1 at AA range: 820-900
  • Applications tips:
Description: A polyclonal antibody for detection of Tie-1 from Human, Mouse, Rat. This Tie-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Tie-1 at AA range: 820-900

Tie-1 Polyclonal Antibody

ABP56395-02ml 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from the Internal region of human Tie-1 at AA range: 820-900
  • Applications tips:
Description: A polyclonal antibody for detection of Tie-1 from Human, Mouse, Rat. This Tie-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Tie-1 at AA range: 820-900

Tie-1 Polyclonal Antibody

ES7394-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against Tie-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

Tie-1 Polyclonal Antibody

ES7394-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against Tie-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

TIE-1 Fc Chimera

PR27153 2 ug
EUR 191

Efficiency Box refill (anti-mouse)

EB-2 27 vials
EUR 101

Mouse Monoclonal anti-PEG (backbone specific) IgG (Clone #2)

PEG13-M-2 100 ug
EUR 482

Anti-Rsk 2/MAPKAP Kinase 1b/RPS6KA3 Antibody

A02215-2 100ug/vial
EUR 334

Anti-COX-2 Rabbit Monoclonal Antibody, Clone#RM348

M00084-2 100uL
EUR 397
Description: Anti-COX-2 Rabbit Monoclonal Antibody, Clone#RM348 tested in WB, IHC, reactive to Human

Tie-2 ELISA Kit (Human) : 96 Wells (OKAG00257)

OKAG00257 96 Wells
EUR 596
Description: Description of target: This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.;Species reactivity: Human;Application: ELISA;Assay info: Quantitative Colorimentric Sandwich ELISA;Sensitivity: 157 pg/mL

Mouse Monoclonal anti-Clostridium difficile toxin A IgG (Clone #2)

CDTA12-M-2 100 ug
EUR 482

Mouse Monoclonal anti-Clostridium difficile toxin B IgG (Clone #2)

CDTB12-M-2 100 ug
EUR 482

Rabbit Anti-human TIE-1 IgG #1, aff pure

TIE11-A 100 ug
EUR 482

Purified Mouse TIE-2 (1-744aa) recombinant control protein for WB

TIE24-C 100 ul
EUR 286

Mouse FGF-2 Recombinant Protein

R00121-2 5ug/vial
EUR 259
Description: FGF basic (FGF2) is a multipotential fibroblast growth factor that stimulates and supports proliferation, migration and differentiation. Mouse FGF basic (FGF-2) Recombinant Protein is purified FGF basic (FGF-2) produced in yeast.

Horse anti-mouse IgG(H+L)-HRP

E22NM02-2 100ug
EUR 343

Horse anti-mouse IgG(H+L)-FITC

E22NM03-2 100ug
EUR 343

Recombinant Human Tyrosine-Protein Kinase Receptor Tie-1/Tie-1 (C-6His)

C502-10ug 10ug
EUR 90
Description: Lyophilized from a 0.2 μm filtered solution of 20mM MES, 150mM NaCl, pH 5.5.

Recombinant Human Tyrosine-Protein Kinase Receptor Tie-1/Tie-1 (C-6His)

C502-1mg 1mg
EUR 1166
Description: Lyophilized from a 0.2 μm filtered solution of 20mM MES, 150mM NaCl, pH 5.5.

Recombinant Human Tyrosine-Protein Kinase Receptor Tie-1/Tie-1 (C-6His)

C502-500ug 500ug
EUR 831
Description: Lyophilized from a 0.2 μm filtered solution of 20mM MES, 150mM NaCl, pH 5.5.

Recombinant Human Tyrosine-Protein Kinase Receptor Tie-1/Tie-1 (C-6His)

C502-50ug 50ug
EUR 171
Description: Lyophilized from a 0.2 μm filtered solution of 20mM MES, 150mM NaCl, pH 5.5.

Polyclonal TIE Antibody (N-term)

APR05992G 0.1ml
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human TIE (N-term). This antibody is tested and proven to work in the following applications:

Human TEK/Tie-2(Angiopoietin Receptor Tie2) ELISA Kit

EH0293 96T
EUR 524.1
  • Detection range: 0.156-10 ng/ml
  • Uniprot ID: Q02763
  • Alias: Tie-2/TEK/CD202B/TIE2/VMCM/VMCM1/Angiopoietin-1 receptor/ANG-R-Tie2/Angiopoietin Receptor Tie2
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Anti-Mouse IgG2a Rabbit Monoclonal Antibody, Clone#RM219

M30946-2 100ug
EUR 398
Description: Anti-Mouse IgG2a Rabbit Monoclonal Antibody, Clone#RM219 tested in WB (nonreduced only), IP, ICC, IHC, FC, ELISA , reactive to Mouse

Anti-Mouse IgG1 Rabbit Monoclonal Antibody, Clone#RM106

M04575-2 100ug
EUR 375
Description: Anti-Mouse IgG1 Rabbit Monoclonal Antibody, Clone#RM106 tested in WB, IP, ICC, IHC, FC, ELISA , reactive to Mouse

Anti-Mouse IgM Rabbit Monoclonal Antibody, Clone#RM109

M07469-2 100ug
EUR 375
Description: Anti-Mouse IgM Rabbit Monoclonal Antibody, Clone#RM109 tested in ICC, IHC, IP, FC, ELISA, reactive to Mouse

Recombinant (CHO cells) Mouse TIE-1 Fc Chimera

RP-704 10 ug
EUR 286

Mouse Pancreas PrimaCell 2: Pancreatic Epithelial Cells

2-82102 1 Kit Ask for price

HRP Conjugated anti-Mouse IgG Super Vision Assay Kit

SV0001-2 100ml/kit
EUR 1065

Custom Anti-Peptide antibodies, 2 peptides (upto 20-aa; synthesis, 2 conjugation, 2 rabbits, 2 ELISA)

ABPEP-20-2 1
EUR 2356

Custom Anti-Peptide antibodies 2 peptides (upto 20-aa, synthesis, 2 conjugation, 2 rabbits, 2 ELISA & 2 Aff. Purif.)

ABPEP-20A-2 1
EUR 3806

Mouse tyrosine kinase with immunoglobulin-like and EGF-like domains 2(Tie-2)ELISA Kit

GA-E0224MS-48T 48T
EUR 336

Mouse tyrosine kinase with immunoglobulin-like and EGF-like domains 2(Tie-2)ELISA Kit

GA-E0224MS-96T 96T
EUR 534

Mouse tyrosine kinase with immunoglobulin-like and EGF-like domains 2(Tie-2)ELISA Kit

QY-E21557 96T
EUR 361

Recombinant Human TIE-1 Fc Chimera

7-04183 1µg Ask for price

Recombinant Human TIE-1 Fc Chimera

7-04184 3µg Ask for price

Recombinant Human TIE-1 Fc Chimera

7-04185 100µg Ask for price

Polyclonal TIE1 / TIE Antibody (C-Terminus)

APR02742G 0.05ml
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human TIE1 / TIE (C-Terminus). This antibody is tested and proven to work in the following applications:

TIE-1 Fc Chimera Protein (Recombinant)

20-abx073607
  • EUR 328.00
  • EUR 4727.00
  • EUR 230.00
  • 10 ug
  • 1 mg
  • 2 µg
  • Shipped within 5-10 working days.

TIE-1 Fc Chimera Protein (Recombinant)

20-abx073608
  • EUR 328.00
  • EUR 4727.00
  • EUR 230.00
  • 10 ug
  • 1 mg
  • 2 µg
  • Shipped within 5-10 working days.

Anti-PRAME Antibody

A06628-2 100ug/vial
EUR 294

Anti-Adam28 Antibody

A06873-2 100ug/vial
EUR 334

Anti-TFF2 Antibody

A07013-2 100ug/vial
EUR 334

Anti-NAT8L Antibody

A07393-2 100ug/vial
EUR 294

Anti-TREML1 Antibody

A07682-2 100ug/vial
EUR 294

Anti-LMTK3 Antibody

A08432-2 100ug/vial
EUR 334

Anti-DRAK2 Antibody

A08711-2 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for DRAK2 Antibody (STK17B) detection.tested for WB in Human, Mouse, Rat.

Anti-IL1F10 Antibody

A09268-2 100ug/vial
EUR 294

Anti-PEF1 Antibody

A09591-2 100ug/vial
EUR 334

Anti-EPB41L5 Antibody

A09638-2 100ug/vial
EUR 334

Anti-RECS1 Antibody

A10501-2 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for RECS1 Antibody (TMBIM1) detection.tested for WB in Human, Mouse, Rat.

Anti-MED18 Antibody

A10600-2 100ug/vial
EUR 334

Anti-IL17B Antibody

A10846-2 100ug/vial
EUR 294

Anti-AOS1 Antibody

A04753-2 100ul
EUR 397
Description: Rabbit Polyclonal AOS1 Antibody. Validated in IF, WB and tested in Human, Mouse, Rat.

Anti-MED14 Antibody

A04799-2 100ug/vial
EUR 294

Anti-HMGN2 Antibody

A04839-2 100ug/vial
EUR 334

Anti-CD84 Antibody

A04872-2 100ug/vial
EUR 334

Anti-PTBP2 Antibody

A05020-2 100ug/vial
EUR 334

We present that one gene regulatory community with fastened topology can show not solely quantitatively but additionally qualitatively completely different phenotypes, relying solely on the native genetic context of its parts. Transcriptional read-through is the primary molecular mechanism that locations one transcriptional unit inside two separate regulons with out the want for complicated regulatory sequences. We suggest that relative order of particular person transcriptional items, with its potential for combinatorial complexity, performs an vital position in shaping phenotypes of gene regulatory networks.